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Galla extract can be used for anti-caries product development

2019-07-25 13:39:25

Galla Chinensis, Rhus chinensis Mill., Rhus potaninii Maxim. or Rhus punjabensis Stew. Var. sinica (Diels) Rehd.et Wils The worm is mainly formed by gallnut mistletoe. Pick in autumn, boil in boiling water or steam until the surface is gray, kill aphids, remove, and dry. Its main active ingredient is gallnut tannin, which has antibacterial and anti-oxidant effects.

According to the shape, it is divided into "belly times" and "corner times".

Recently, researchers at the West China College of Stomatology, Sichuan University, after testing hundreds of Chinese herbal medicines, found that the extract of Rhus chinensis Mill. has strong antibacterial ability and can inhibit the acid production of caries-related bacteria. Prevent tooth decay and mineralization of teeth. Therefore, the active ingredient contained in the gallnut extract can be used in natural anti-caries products.

In this study, the researchers analyzed the various active ingredients contained in the gallnut extract by liquid chromatography-mass spectrometry (LC-MS). Firstly, a variety of microbial biofilm models were used to detect the strong antibacterial ability of Galla chinensis, which can also produce regenerative plaque biofilm in vivo. Secondly, the in vitro pH cycle test detected gallnut anti-tooth mineralization, which can simulate Periodic changes in pH in the mouth. Finally, the researchers compared water extract components (GEC), ethanol extract (eGCG) and tannic acid. It was found that all of these three components contained high levels of total polyphenols, but eGCG and tannic acid were more effective in inhibiting enamel demineralization, acid and biofilm formation.

The latest research also shows that Galla chinensis extract also has antiviral, anti-cancer, liver-protecting, anti-diarrhea and antioxidant activities. In order to maintain a healthy mouth, the oral environment must be relatively neutral. When the entire oral environment is in a more acidic environment, it is easy to breed tooth decay or other oral diseases. Galla extract can be used not only to inhibit the acid production of caries-related bacteria, but also to make teeth resistant to acidic environments.

Rickets is a chronic bacterial disease that occurs in hard tissues of teeth. It has a high incidence and a wide distribution, which seriously affects human oral and general health. The use of fluorochemicals is currently the most common method of preventing rickets. Although fluoride has a certain effect in preventing and reducing tooth decay, it is not a perfect solution and requires other measures. In addition, the use of fluorochemical preparations has significant limitations, such as causing dental fluorosis and skeletal fluorosis. Based on this research, researchers are currently developing new oral care products. Galla chinensis extract is rich in tannic acid and provides strong application potential in the prevention of dental caries.

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